A New Hampshire family comes apart at the seams when Angie Voorster, an ostensibly perfect high school senior and swim team star falls off the edge of mental stability. Among those affected are Pieter, Angie's emotionally inarticulate father; her mother, Jordana, 15 years Pieter's junior and seeking solace in the arms of a younger man; and Angie's younger brother, Luke, who becomes his sister's keeper. Over the next several years, bipolar Angie struggles to adjust to life derailed by mental illness, ever-changing prescriptions and their side effects.